Dados do Trabalho

Title

SEMINAL PARAMETERS IN SINGLE FRESH EMBRYO TRANSFERS: ARE THEY BETTER IN POSITIVE CLINICAL PREGNANCY?

Objective

To evaluate the association between seminal parameters and the presence of pregnancy in single fresh embryo transfers.

Methods

A retrospective cohort study was performed in a Reproductive Medicine Center from January 2020 to December 2022. A total of 194 single fresh embryo transfers were evaluated. The embryos were cultivated in a time-lapse incubator (Embryoscope®, Vitrolife®) after Intracytoplasmic sperm injection (ICSI). The samples were divided into two groups (pregnancy versus non-pregnancy). Seminal parameters (sperm motility, concentration, morphology abnormal and abnormal head, midpiece and tail morphology) were analyzed between groups. Frozen oocytes and preimplantation genetic testing (PGT) embryos were excluded as well as all the percutaneous epididymal sperm aspiration (PESA) and testicular sperm aspiration or extraction (TESA/TESE). The data were presented as mean and standard error (SE) and as mean and standard deviation (SD). ANCOVA and Student t tests were applied, and data were adjusted for female age.

Results

The mean male age according to pregnancy versus non-pregnancy was, respectively, 39.7±6.2 and 39.9±6.9 years (p=0.823). When comparing seminal parameters in both groups, no statistical difference was found. The comparative analysis of seminal parameters between the two groups are shown in Table 1.

Conclusion

When the maternal age is adjusted, none of the seminal parameters seem to influence the pregnancy outcomes. Perhaps the low number of embryos transferred have limited the outcome of the results. More studies with larger samples should be conducted in order to identify any possible significant difference.

Keywords

Seminal parameters; embryo transfer; pregnancy outcomes.

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