Dados do Trabalho

Title

AUTOMATIC EMBRYO SCORING USING THE KIDSCORE ALGORITHM AND NEONATAL OUTCOMES

Objective

Time lapse technology is bringing new perspectives to the relationship between embryos' morphokinetics and implantation rates after assisted reproduction techniques (ART). The KIDscoreTM D5 (KS5®) algorithm has reported that a higher KIDScore is related to higher euploid embryos, which could lead to higher chances of implantation. However, data relating neonatal outcomes and the KS5 algorithm are scarce. Thus, the objective of the present study was to analyze if there is any association between KIDScore and neonatal outcomes.

Methods

Retrospective observational study performed at a reproductive medicine center, using data collected between 2020 and 2022. A total of 66 live births resulting from 197 single fresh blastocysts transferred cycles were included for analysis. All embryos were cultivated in a time-lapse incubator (Embryoscope®, Vitrolife®) and received a KS5. The sample was stratified by KS5: G1 (1-6.9) and G2 (7.0-9.9). T-test and chi-square test were used for analysis, considering p<0.05.

Results

Results regarding the comparison between G1 vs. G2, are presented in Table 1 and table 2.

Conclusion

It was observed that when the KS5 was equal or higher than 7, the birthweight was lower, and the percentage of SGA was higher. However the lower birth weight may have other parameters related like endometrium, maternal endothelial disease, and so, the data could be better analyzed with large samples and maternal characteristics included. Besides the birthweigh and percentile, there were no longer differences between groups.

Keywords

Birth weight; ICSI; embryo development; KIDscore D5.

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