Dados do Trabalho

Title

Evaluation of Seminal Parameters Acoording to WHO 2021 Guideline in a Obese Population

Objective

Infertility can occur due to various factors, and currently, obesity has become a serious problem when it comes to fertility. In men, it causes alterations in the levels of crucial sex hormones. It increases estradiol levels and reduces testosterone levels, which may be related to the accumulation of adipose tissue. This can potentially compromise sperm production.
The general objective of this study was to determine if semen parameters, according to the WHO 2021 guidelines, are negatively affected by obesity in a subset of individuals

Methods

For the collection of semen samples, participants underwent a brief questionnaire, containing information about age, weight, height, and some questions about daily habits, such as drug and anabolic steroid use. The samples were collected through masturbation in a specific and private room using a disposable and sterile plastic container. Patients were sexually abstinent for two to three days before the collection. The analysis was performed through a semen analysis, following the criteria set by the World Health Organization (2021). The analysis included the use of a Micrometric Reticule to evaluate sperm size, macroscopic analysis of the sample (color, volume, liquefaction, viscosity, and pH), and microscopic analysis of the sample (concentration, motility, morphology, and vitality). They were divides into three groups: gruop 1 with normal BMI, group 2 with overweight BMI, and group 3 with obese BMI.

Results

The study found a negative relationship in the value of morphology (p=0.008) in group 3, which consisted of individuals classified as obese. This suggests a decrease in sperm quality in obese patients. The results did not show a relationship between BMI and the rest of the evaluated semen parameters.

Conclusion

In conclusion, the study indicates that BMI is related to a decrease in normal morphology in individuals with a BMI above the ideal range for their height, specifically, obese individuals in the studied population. The other semen parameters did not show significant differences between the groups.

Keywords

Male infertility. Obesity. Semen