Dados do Trabalho

Title

Impact of the use of the zymot plate on the outcomes of Assisted Reproduction procedures at an in vitro fertilization clinic in Northeastern Brazil

Objective

To analyze and relate the use of the Zymot technique in assisted reproduction procedures, as well as its influence on parameters such as the rate of fertilized oocytes and quality of embryonic development, associating these data with the performance indicators of the Vienna Consensus.

Methods

This is a retrospective study that used a pre-formed data sheet from a private Assisted Reproduction clinic in northeastern Brazil, using data from October 2020 to June 2023, totaling 69 cases, 1 of which was excluded from the research because calcium was used in the eggs. The mean age of women was between 38 years and normal weight, and the mean age of men was between 46 years and overweight. The seminal processing technique used in all cases was the Zymot.

Results

After analyzing the data, it was possible to observe that the results of the parameters of the rates of the clinical indicators using the Zymot technique to process the semen, in order to obtain spermatozoa with better motility and with low levels of sperm DNA fragmentation, presented a good correlation with the quality indicators of the Vienna Consensus. The fertilization rate was 74.8%, the cleavage rate was 100%, and blastulation was 57.9%.

Conclusion

Female age may have an influence on the maturity rate parameter, while our findings suggest that male age has a greater impact on sperm DNA fragmentation and due to this, the zymot technique was used to minimize fragmentation and this way to improve the quality of fertilization and embryonic development. Thus, we can state that the rates of the indicators were close with the use of the Zymot technique when compared with the rates of the Vienna Consensus.

Keywords

Zymot, Vienna Consensus, In vitro fertilization, sperm DNA fragmentation